Reza Fardid has completed his PhD at the age of 33 years from Mashhad University of Medical Sciences. He has published more than 25 papers in reputed journals and has been supervising more than 10 MS.c. students.

Nobody can deny the deleterious health effects of high doses of radiation, although there is no consensus about the health impact of low dose of ionizing radiation. This study aimed to discuss the effect a range of ionizing radiation doses (including low doses) on the changes of gene expression and serum protein levels of two immune factors TGF-β and IFN-γ in rats. \r\nAfter 24 hours of irradiation of rats with the doses of 1000, 500, 100, 50 and 20mGy, the gene expression of TGF-β and IFN-γ in lymphocytes was assessed using QPCR. Besides, the protein level of these two factors in lymphocyte plasma was determined by ELISA kits.\r\nSignificant increases in the expression levels of TGF-β and IFN-γ genes were observed by increasing the dose from 100mGy to 500mGy and then 1000mGy compared to the controls (p<0.05). The ELISA tests showed significant differences in the serum level of TGF-β cytokine in the dose of 1000mGy, while the serum level of IFN-γ cytokine showed significant differences in doses of 20mGy and 1000mGy compared to the controls (p<0.05).\r\nThe results of this study showed the changes in the expression of TGF-β and IFN-γ genes after irradiation more than 100mGy in lymphocytes compared to the control group; , the changes in the serum levels of these cytokines only occurred in the specific doses compared to the control group.\r\n

Ayman mokhtar had completed master degree at the age of 35 years from mansoura University,\r\n\r\n

To survey computed tomography (CT) radiation dose associated with non-contrast spiral Multislice computed tomography exam in our institute.\r\n METHODS: Survey radiation dose for non-contrast scan of abdomen and pelvis was retrospectively evaluated in urology nephrology center (UNC) - Mansoura University using a 64-detector CT scanner. Detailed parameters for 362 consecutive examinations, including the patient weight, height, CTD volume (CTDIvol), scan length, and dose length product (DLP) were recorded from the dose report. Effective dose (E) was estimated for each patient. The differences between E doses were statistically analyzed using SSPS. \r\nRESULTS: Patients body mass index (BMI) was 13.4 to 51.42 (Average BMI 29.5 kg/m). Patients dose data (1 scan phase for each patient) from dose information: the median value of DLP was 586.45 mGy-cm (83.30 mGy-cm - 1179.70 mGy-cm), median value of CTDI vol was 12.07 (2.20 mGy - 23.9 mGy), median value of mAs used was 186.50 (34mAs - 334mAs). Effective dose range was (1.1 to 16.5mSv) according to international commission of radiological protection (ICRP) 106 and according to ICRP60 the range was (1.3 to 18.93mSv). Maiden value of frequent CT examinations for the same patient was 2 (min 1 scan/year & max 11 scan / year). CT dose variation was highly significant (p value <0.01) depending on high variation on mAs with (r=0.98). CT dose was moderate depending on MBI (r= 0.55).\r\nCONCLUSION: There was statistically highly significant variation in effective radiation doses associated with non-contrast CT scan of abdomen and pelvis. The reason for this variation must be avoided.\r\n