Medical Physics

Biography

Biography: Javier Rodríguez

Abstract

Introduction: A new diagnostic methodology based on probability and entropy proportions was developed. This methodology has been successful on cardiac dynamic evaluation. Objectives: To apply the diagnostic methodology to the arrhythmic dynamic, evaluating the evolution from normality to acute disease. Method: 75 holter were studied; these records had clinical diagnosis of normality and stable and unstable cardiac arrhythmia. An attractor for each dynamics is generated from the values, obtained each hour, of maximum and minimum frequency and number of beats per minute. From the calculation of the proportions of entropy, the status of each dynamic was mathematically evaluated; showing how close or far is of normal dynamics. The sensibity, specificity and Kappa coefficient were calculated. Results: The normal cases had values into the expected limits. In the same way the cases with stable and unstable cardiac arrhythmia had values for the proportions entropy into disease limits. values of sensibility and specificity of the new method compared with the conventional diagnosis were 100% and the Kappa coefficient value was 1. Conclusions: The results showed the clinical applicability of the diagnostic method, it allowed the quantitative evaluation of each particular dynamics, showing how far is each arrhythmic dynamics of normality. Key words: Entropy, Probability, holter, heart disease, arrhythmia, cardiac dynamics.